The loan is a vote of confidence in Uzbekistan's reforms.
American investments contribute significantly to the Kazakh economy, officials and analysts in Nur-Sultan say.
A modern textile industry will help Afghanistan improve its economy and stability, create jobs and start exports, say specialists.
The CASA-1000 aims to deliver summer surplus hydro-power from Kyrgyzstan and Tajikistan to Afghanistan and Pakistan, which suffer from chronic electricity shortages.
A government-backed effort seeks to increase wine exports and double the area under cultivation by the end of 2021.
With 210 million hectares of agricultural land, second in the world, there are 'colossal opportunities' in Kazakhstan in this field.
The USAID-funded forum reflects growth in Central Asia's openness to regional and international trade, according to the organisers.
China's economic investment in Central Asian threatens Russia's interests and influence in the region, analysts say.
Russia's coercive economic policies have led to a massive shortage of sugar in Kazakhstan, threatening the livelihoods of local businesses and harming the nation's citizens.
Jobs are giving previously unemployed young Kazakhs an outlet for their energies and a source of income.